| dc.contributor.advisor | Rozas, Isabel | |
| dc.contributor.author | Corcoran, Jonathan | |
| dc.date.accessioned | 2019-04-29T15:06:56Z | |
| dc.date.available | 2019-04-29T15:06:56Z | |
| dc.date.issued | 2007 | |
| dc.identifier.citation | Jonathan Corcoran, 'Synthesis, biological evaluation and subsequent SAR of four novel families of alkyliphatic twin drugs', [thesis], Trinity College (Dublin, Ireland). School of Chemistry, 2007, pp 226 | |
| dc.identifier.other | THESIS 8398 | |
| dc.identifier.uri | http://hdl.handle.net/2262/86271 | |
| dc.description.abstract | The I2-IBS is a well known binding site widely distributed in the body of both animals and humans. It is suspected that they are an allosteric binding site of MAO-B. They have also been linked to several conditions such as Alzheimer’s and neuro protection. Their main physiological function appears to be the ability of I2-IBS ligands to attenuate the tolerance to opiod drugs. This link between the I2-IBS and the u-opioid receptor system has made I2-IBS binding sites of pharmalogical importance. | |
| dc.format | 1 volume | |
| dc.language.iso | en | |
| dc.publisher | Trinity College (Dublin, Ireland). School of Chemistry | |
| dc.relation.isversionof | http://stella.catalogue.tcd.ie/iii/encore/record/C__Rb13330987 | |
| dc.subject | Chemistry, Ph.D. | |
| dc.subject | Ph.D. Trinity College Dublin | |
| dc.title | Synthesis, biological evaluation and subsequent SAR of four novel families of alkyliphatic twin drugs | |
| dc.type | thesis | |
| dc.type.supercollection | thesis_dissertations | |
| dc.type.supercollection | refereed_publications | |
| dc.type.qualificationlevel | Doctoral | |
| dc.type.qualificationname | Doctor of Philosophy (Ph.D.) | |
| dc.rights.ecaccessrights | openAccess | |
| dc.format.extentpagination | pp 226 | |
| dc.description.note | TARA (Trinity's Access to Research Archive) has a robust takedown policy. Please contact us if you have any concerns: rssadmin@tcd.ie | |
