| dc.contributor.advisor | Rowan, Michael | |
| dc.contributor.author | Barry, Andrew | |
| dc.date.accessioned | 2019-10-17T10:54:43Z | |
| dc.date.available | 2019-10-17T10:54:43Z | |
| dc.date.issued | 2010 | |
| dc.identifier.citation | Andrew Barry, 'Antibodies prevent the acute inhibition of long term potentiation by amyloid beta in the rat hippocampus', [thesis], Trinity College (Dublin, Ireland). School of Medicine. Discipline of Pharmacology & Therapeutics, 2010, pp 192 | |
| dc.identifier.other | THESIS 9086 | |
| dc.identifier.uri | http://hdl.handle.net/2262/89781 | |
| dc.description.abstract | The present study investigated the mechanisms underlying the inhibition of long-term
potentiation (LTP) of excitatory synaptic transmission by amyloid beta (Aβ) in the
anaesthetized rat hippocampus. The role of soluble Aβ assemblies was investigated.
Furthermore, we explored the ability of anti-oligomer and anti-fibril antibodies to prevent the
inhibition of LTP by different peptides. Finally, we studied the role of the cellular prion
protein (PrPc) in Aβ-mediated inhibition of LTP. | |
| dc.format | 1 volume | |
| dc.language.iso | en | |
| dc.publisher | Trinity College (Dublin, Ireland). School of Medicine. Discipline of Pharmacology & Therapeutics | |
| dc.relation.isversionof | http://stella.catalogue.tcd.ie/iii/encore/record/C__Rb14628658 | |
| dc.subject | Pharmacology and Therapeutics, Ph.D. | |
| dc.subject | Ph.D. Trinity College Dublin. | |
| dc.title | Antibodies prevent the acute inhibition of long term potentiation by amyloid beta in the rat hippocampus | |
| dc.type | thesis | |
| dc.type.supercollection | thesis_dissertations | |
| dc.type.supercollection | refereed_publications | |
| dc.type.qualificationlevel | Doctoral | |
| dc.type.qualificationname | Doctor of Philosophy (Ph.D.) | |
| dc.rights.ecaccessrights | openAccess | |
| dc.format.extentpagination | pp 192 | |
| dc.description.note | TARA (Trinity’s Access to Research Archive) has a robust takedown policy. Please contact us if you have any concerns: rssadmin@tcd.ie | |
