Design, synthesis and photophysical evaluation of novel 1 ,8-naphthalimide Tröger's base derivatives
Citation:
Samantha Murphy, 'Design, synthesis and photophysical evaluation of novel 1 ,8-naphthalimide Tröger's base derivatives', [thesis], Trinity College (Dublin, Ireland). School of Chemistry, 2012, pp 314Download Item:
Abstract:
This thesis entitled 'Design, Synthesis and Photophysical Evaluation of Novel 1,8-
Naphthalimide Based Troger's Bases' is divided into five chapters. The first chapter provides
a brief description of the structure of DNA and the different modes by which molecules may
interact with it. In addition, an introduction is given to the discovery and development of 1,8-
naphthalimides as anti-cancer agents. Such research represents an important contribution to
the design of potent therapeutic agents, some of which have even entered clinical trials.
Author: Murphy, Samantha
Advisor:
Gunnlaughsson, ThorfinnurQualification name:
Doctor of Philosophy (Ph.D.)Publisher:
Trinity College (Dublin, Ireland). School of ChemistryNote:
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Full text availableKeywords:
Chemistry, Ph.D., Ph.D. Trinity College Dublin.Metadata
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