| dc.contributor.author | Connon, Stephen | |
| dc.date.accessioned | 2021-10-20T15:53:13Z | |
| dc.date.available | 2021-10-20T15:53:13Z | |
| dc.date.issued | 2018 | |
| dc.date.submitted | 2018 | en |
| dc.identifier.citation | Craig, R. and Sorrentino, E. and Connon, S.J., Enantioselective Alkylation of 2-Oxindoles Catalyzed by a Bifunctional Phase-Transfer Catalyst: Synthesis of (â )-Debromoflustramine B, Chemistry - A European Journal, 24, 18, 2018, 4528-4531 | en |
| dc.identifier.other | Y | |
| dc.identifier.uri | http://hdl.handle.net/2262/97401 | |
| dc.description.abstract | A new bifunctional phase-transfer catalyst that employs hydrogen bonding as a control element was developed to promote efficient enantioselective SN2 reactions for the construction all-carbon quaternary stereocenters in high yield and excellent enantioselectivity (up to 97 % ee) utilizing the alkylation of a malleable oxindole substrate. The utility of the methodology was demonstrated through a concise and highly enantioselective synthesis of (−)-debromoflustramine B. | en |
| dc.format.extent | 4528-4531 | en |
| dc.language.iso | en | en |
| dc.relation.ispartofseries | Chemistry - A European Journal; | |
| dc.relation.ispartofseries | 24; | |
| dc.relation.ispartofseries | 18; | |
| dc.rights | Y | en |
| dc.subject | debromoflustramine B | en |
| dc.subject | Phase-transfer | en |
| dc.subject | Enantioselectivity | en |
| dc.title | Enantioselective Alkylation of 2-Oxindoles Catalyzed by a Bifunctional Phase-Transfer Catalyst: Synthesis of (− )-Debromoflustramine B | en |
| dc.type | Journal Article | en |
| dc.type.supercollection | scholarly_publications | en |
| dc.type.supercollection | refereed_publications | en |
| dc.identifier.peoplefinderurl | http://people.tcd.ie/connons | |
| dc.identifier.rssinternalid | 189079 | |
| dc.identifier.doi | http://dx.doi.org/10.1002/chem.201800313 | |
| dc.rights.ecaccessrights | openAccess | |
