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dc.contributor.advisorMartin, Cara
dc.contributor.authorWhite, Christine
dc.date.accessioned2017-02-09T14:56:51Z
dc.date.available2017-02-09T14:56:51Z
dc.date.issued2012
dc.identifier.citationChristine White, 'HPV mRNA and p16[ink4a] / Ki-67 detection for improved diagnosis and management of cervical neoplasia in smokers', [thesis], Trinity College (Dublin, Ireland). School of Medicine. Discipline of Histopathology & Morbid Anatomy, 2012, pp 314
dc.identifier.otherTHESIS 10158
dc.identifier.urihttp://hdl.handle.net/2262/79394
dc.description.abstractPersistent infection with high risk human papillomavirus (HR HPV) is the main etiological agent in the development of cervical cancer. The use of HPV DNA testing in cervical screening programs is becoming increasingly common worldwide. However, due to the high prevalence of transient HPV infections in low grade lesions, HPV DNA testing is limited. Early evidence suggests that detection of HPV E6/E7 mRNA transcripts and p16 INK4A/Ki-67 over expression is more indicative of a clinically relevant infection than HPV DNA testing.
dc.format1 volume
dc.language.isoen
dc.publisherTrinity College (Dublin, Ireland). School of Medicine. Discipline of Histopathology & Morbid Anatomy
dc.relation.isversionofhttp://stella.catalogue.tcd.ie/iii/encore/record/C__Rb15361182
dc.subjectHistopathology, Ph.D.
dc.subjectPh.D. Trinity College Dublin
dc.titleHPV mRNA and p16[ink4a] / Ki-67 detection for improved diagnosis and management of cervical neoplasia in smokers
dc.typethesis
dc.type.supercollectionthesis_dissertations
dc.type.supercollectionrefereed_publications
dc.type.qualificationlevelDoctoral
dc.type.qualificationnameDoctor of Philosophy (Ph.D.)
dc.rights.ecaccessrightsopenAccess
dc.format.extentpaginationpp 314
dc.description.noteTARA (Trinity’s Access to Research Archive) has a robust takedown policy. Please contact us if you have any concerns: rssadmin@tcd.ie


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